Chronic disease epidemic is real! We, as a society must change the way we approach to nutrition, otherwise chronic diseasestatistics predictions are grim.
Obesity constitutes a significant health burden worldwide, becoming root cause of large number of health problems, such as dyslipidemias, type 2 Diabetes, non-alcoholic fatty liver disease, some types of cancers, causing health, social and economic burden across the globe.
Knowledge on how food interacts with our genes, and how our body responds to these interferences, along with epigenetic factors, is what Nutrigenomics’ promise consists of. This rapidly evolving scientific field is tailoring the framework for the genotype driven dietary recommendations, evidence-based solutions to dietary interventions and hopefully tackling chronic disease epidemic worldwide.
Regarding type 2 Diabetes, there’s robust and growing evidence, showing some food component and genes’ beneficial interaction. For instance, bioactive substances such as quercetin, genistein, resveratrol, catechins, curcumin and anthocyanins have shown beneficial and protective effects related to type 2 Diabetes. Through affecting insulin secretion and signaling, inflammatory processes, oxidative stress, glucose and lipid metabolism, the interaction of these active substances and relevant genes produces beneficial effect in the prevention and management of type 2 Diabetes.
Nutrigenomics connects nutrition to genome and studies the bidirectional interactions between genes and our diet, specifically exploring the genetic relationship of the food we eat, environmental factors, lifestyle and its correlation to prevention and treatment of chronic diseases.
After the completion of Human Genome Project ( 1990-2003), where the DNA sequence of the entire human genome was mapped out, the era of precision medicine took off and nutrient-gene interplay concept was born.
Imagine if your diet is not optimal and is more of like SAD ( Standard American Diet), you will most likely have variety of nutritional deficiencies sending those poor signals to your genesto not function at an optimal level.